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The obesity epidemic is spreading around the world and the U.S. Centers for Disease Control and Prevention (CDC) warn that approximately two thirds of American adults are now overweight or obese. Natural nutrients that help control appetite offer an effective tool in the battle of the bulge. Recent obesity research has discovered powerful botanicals that have appetite-suppressing effects and promote weight loss. The following supplements offer natural appetite control that help decrease caloric intake, suppress food cravings and enhance satiety (the feeling of satisfaction).

Satiereal Saffron Extract - the Satiereal extract form is derived from the stigma of the saffron flower. A rare and popular spice, the pure extract of the flower stigmas has shown in recent clinical studies to have powerful effects as an appetite suppressant. The biochemical mechanism appears to work on the brain's serotonin receptors, reducing cravings and stopping hunger and increased appetite in its tracks. By modulating the mood effects of serotonin in the same way as eating unhealthy or excessive amounts of food, pure saffron extract can stop cravings and help users lose weight. Most users report an added bonus of increased feelings of calmness, and less stress-related snacking.

  1. Conjugated Linoleic Acid (CLA)-Several studies have reported that CLA improves fat metabolism, increases lean body mass and reduces appetite, without a change in diet or exercise.

  2. Fiber- Water-soluble fiber has multiple weight loss benefits. Research reports that high fiber intake diminishes appetite, increases feelings of fullness, and improves weight control.

  3. Chromium picolinate- An eight-week randomized, double-blind, placebo-controlled study found that supplementation with a natural dietary compound containing chromium reduced appetite, inhibited fat synthesis, and decreased body weight in 60 moderately obese participants.

  4. Korean Pine Nut (Pinolenic Acid)- Penolenic acid, an extract of the Korean Pine Nut, has been found to significantly suppress appetite and enhance satiety. A randomized, double-blind, placebo-controlled study found that supplementation with pine-nut derived pinolenic acid reduced food intake by 36 percent in overweight participants.

  5. Hydroxy citric acid (HCA), an extract from the Malabar tamarind fruit, inhibits the conversion of carbohydrates into fat, reduces appetite, and promotes weight loss.

  6. Hydroxytryptophan (5-HTP)-Studies suggest that 5-HTP enhances satiety, leading to decreased appetite and caloric intake at meals and weight loss.

Saffron Extract Pure contains HCA, Chromium picolinate, and Satiereal saffron.

  1. Satiereal, a Crocus sativus L extract, reduces snacking and increases satiety in a randomized placebo-controlled study of mildly overweight, healthy women," Nutr Res, 2010; 30(5): 305-13.

  2. MacLean DB and Luo LG. Increased ATP content/production in the hypothalamus may be a signal for energy-sensing of satiety: studies of the anorectic mechanism of a plant steroidal glycoside. Brain Res 2004 Sep10; 1020(1-2):1-11.

  3. Gaullier JM et al. Conjugated linoleic acid supplementation for 1 year reduces body fat mass in healthy overweight humans. Am J Clin Nutr 2004 Jun;79(6):1118-25.

  4. Gaullier JM et al. Supplementation with conjugated linoleic acid supplementation for 24 months is well tolerated by and reduces body fat mass in healthy overweight humans. J Nutr 2005 Apr;135(4):778-894.

  5. Lairon D et al. Dietary fiber intake and risk factors for cardiovascular disease in French adults. AJCN Dec 2005;82(6):1185-1194.

  6. Preuss HG, Bagchi D et al. Effects of a natural extract of (-)-hydroxycitric acid (HCA-SX) and a combination of HCA-SX plus niacin-bound chromium and Gymnema sylvestre extract on weight loss. Diabetes Obes Metab . 2004 May;6(3):171-180.

  7. Hoeger WW, Harris C et al. Four-week supplementation with a natural dietary compound produces favorable changes in body composition. Adv Ther . 1998 Sep;15(5):305-314.

  8. Causey JL. Korean pine nut fatty acids induce satiety-producing hormone release in overweight human volunteers. Study presented at: American Chemical Society National Meeting & Exposition; March 26-30, 2006; Atlanta, GA.

  9. Pizzorno J and Murray M. Encyclopedia of Natural Medicine, New York: Prima, 1998: 686-693.


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