Lipo 6® is a dietary supplement that promises to burn fat, control appetite, increase energy, and promote weight loss. Lipo 6® includes nutrients derived from herbs and botanicals that may help promote weight loss and enhance thermogenesis (calorie expenditure). The supplement contains synephrine (citrus aurantium extract), caffeine, guggulsterones, biosperine and yohimbe.
The manufacturer, Nutrex, has not conducted clinical studies of Lipo 6® . However, research suggests that synephrine and caffeine may work synergistically to increase thermogenic effects and promote weight loss. In addition, guggulsterones (an Indian tree resin extract) may stimulate the thyroid gland and affect thyroid hormones. Biosperine (black pepper extract) may enhance the absorption of supplements in the body.
The U.S. Food and Drug Administration (FDA) has warned that yohimbe (an African tree bark extract), used as an aphrodisiac, is associated with potentially harmful side effects. "Serious adverse effects including renal failure, seizures and death, have been reported to FDA with products containing yohimbe and are currently under investigation," states the FDA.
Lipo6® has an extensive warning on its label. It recommends that Lipo6® not be used by women who are pregnant or nursing. "Consult your physician prior to use if you have a medical condition, including but not limited to, heart, liver, kidney, or thyroid disease, psychiatric disorders, difficulty urinating, diabetes, high blood pressure, cardiac arrhythmia, recurrent headaches, enlarged prostate or glaucoma," the Lipo 6® label states.
Nutrex Ephedra Free Lipo 6 Fat Burner Review, UltimateFatBurner, online:
Illnesses and Injuries Associated with the Use of Selected Dietary Supplements, FDA.gov, online:
Lipo-6 Liqui-caps, Netrition.com, online: