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Zetacap is a dietary supplement promoted as a 'gastric bypass' pill that allegedly expands in the stomach, creating a sense of fullness and reducing food intake. However, Zetacap's manufacturer, Selmedica Healthcare, has been served with a U.S. Food and Drug Administration (FDA) warning letter for false and misleading statements.  

"These statements are false and misleading and misbrand the products DigestrinT, GoutinT, LiporexT, ChitorexT, ZetacapT, WelatoninT under 403(a)(1) of the Act [21 U.S.C. 343(a)(1)] because they state that the ingredients contained in these products are generally recognized as safe and effective when, in fact they are not," writes Joseph R. Baca, Director, FDA Office of Compliance. "Furthermore, they imply that FDA reviews and approves dietary supplement products and/or their ingredients. In fact, FDA does not approve dietary supplements or their ingredients." 

Zetacap contains ingredients that don't have much to do with weight loss such as St. John's wort (used for depression), echinacea (used for immunity), and valerian (used as a sedative). Their main ingredient is a "nano-fiber" blend of nutrients such as cassia angustifolia and xanthum gum. Studies have shown that fiber can reduce appetite and food intake and promote weight loss. However, many experts recommend obtaining fiber primarily from foods with a high-fiber content such as whole grains, vegetables, and fruits. Inexpensive fiber supplements can also be obtained. However, Zetacap is substantially more expensive, costing $75 for a 30-day supply.


  1. USA Chemicals, Inc. Warning Letter, FDA.gov, March 1, 2005:
  2. http://www.fda.gov/foi/warning_letters/g5239d.htm

  3. Zetacap Official Site, Zetacap:
  4. http://www.zetacap.com

  5. Lose weight with Zetacap, Zetabody.com:
  6. http://www.zetabody.com

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